Interleukin-1b enhances retinoic acid-mediated expression of bone-type alkaline phosphatase in rat IEC-6 cells
نویسندگان
چکیده
TAKESHI NIKAWA, MADOKA IKEMOTO, KAORI TOKUOKA, SHIGETADA TESHIMA, DAVID H. ALPERS, YOSHIHIRO MASUI, KYOICHI KISHI, AND KAZUHITO ROKUTAN Department of Nutrition, School of Medicine, University of Tokushima, Tokushima 770-8503, Japan; Department of Internal Medicine, Division of Gastroenterology, Washington University School of Medicine, St. Louis, Missouri 63110; and Therapeutic Application Development Group, Otsuka Pharmaceutical Company, Tokyo 101-8535, Japan
منابع مشابه
Interleukin-1beta enhances retinoic acid-mediated expression of bone-type alkaline phosphatase in rat IEC-6 cells.
We previously showed that vitamin A upregulated the expression of bone-type alkaline phosphatase (ALP) in fetal rat small intestine and rat intestinal IEC-6 cells. In this study, we examined interactions between retinoic acid (RA) and several growth factors/cytokines on the isozyme expression in IEC-6 cells. Epidermal growth factor and interleukins (ILs)-2, -4, -5, and -6 completely blocked the...
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